China Doxycycline Hyclate masana'antun da masu kaya |CPF

Doxycycline Hyclate

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Sunan API	Nuni	Ƙayyadaddun bayanai	Farashin DMF	EU DMF	CEP
Doxycycline Hyclate	Magungunan rigakafi	USP/EP	13771	√

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Fage

Doxycycline hyclate maganin rigakafi ne [1].

Doxycycline hyclate wani abu ne na tetracycline kuma yana da ayyukan anti-mai kumburi da antimicrobial.Doxycycline yana hana kwafin kwayar cutar dengue a cikin vitro tare da yanayin dogaro da zafin jiki.Ƙimar IC50 ita ce 52.3μM a 37 ° C da 26.7μM a 40 ° C.Yana hana cutar dengue ta hanyar hana NS2B-NS3 serine protease na kwayar cutar.60μM doxycycline yana rage CPE na kwayoyin cutar DNEV2 [1].

Ana samun Doxycycline a matsayin mai hana MMP.Maganin Doxycycline yana rage matakan MMP-8 da -9 kuma yana hana maganganun nama MMP-2 da MMP-9.Bugu da ƙari, jiyya tare da doxycycline yana rage yawan abubuwan da ke faruwa na intracranial aneurysms.An kuma bayar da rahoton Doxycycline a matsayin wakili mai hana kumburi dangane da hanawar matrix metalloproteinases.Bugu da ƙari, doxycycline yana da aikin antimalarial mai ƙarfi tare da ƙimar IC50 na 320nM a 96h in vitro [2, 3].

Magana:
[1] Rothan HA, Mohamed Z, Paydar M, Rahman NA, Yusof R. Tasirin hanawa na doxycycline akan kwafin kwayar cutar dengue a cikin vitro.Arch Virol.2014 Afrilu; 159 (4): 711-8.
[2] Maradni A, Khoshnevisan A, Mousavi SH, Emamirazavi SH, Noruzijavidan A. Matsayin matrix metalloproteinases (MMPs) da masu hana MMP akan aneurysms intracranial: labarin bita.Med J Islam Jamhuriyar Iran.2013 Nuwamba; 27 (4): 249-254.
[3] Draper MP, Bhatia B, Assefa H, Honeyman L, Garrity-Ryan LK, Verma AK, Gut J, Larson K, Donatelli J, Macone A, Klausner K, Leahy RG, Odinecs A, Ohemeng K, Rosenthal PJ, Nelson ML.In vitro da in vivo ingancin maganin zazzabin cizon sauro na ingantattun tetracyclines.Magungunan Antimicrob Agents Chemother.2013 Yuli; 57 (7): 3131-6.

Bayani

Doxycycline (hyclate) (Doxycycline hydrochloride hemiethanolate hemihydrate), maganin rigakafi, shine mai hana baki da kuma faffadan metalloproteinase (MMP) mai hanawa[1].

Gwajin asibiti

Lambar NCT	Mai tallafawa	Yanayi	Ranar farawa	Mataki
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NCT02913118	Qingfeng Pharmaceutical Group	Ciwon huhu da Al'umma Suka Samu	Yuli 2016	Mataki na 4
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NCT01867294	Cibiyar Nazarin Ciwon Kankara ta Ƙasashen Duniya (NCI)	Advanced Malignant Neoplasm \| Rikicin Jiki	31 ga Agusta, 2012	Mataki na 2
Saukewa: NCT01677286	Jami'ar Boston	Amyloidosis	Yuli 2012	Mataki na 2
Saukewa: NCT00511875	Thomas Gardner \| Gidauniyar Bincike kan Ciwon Ciwon Yara \| Milton S. Hershey Medical Center	Ciwon Ciwon Jiki	Yuli 2008	Mataki na 2
Saukewa: NCT04108897	Jami'ar Johns Hopkins	Rosacea	Satumba 17, 2019	Farkon Mataki na 1
Saukewa: NCT00631501	Kaunas University of Medicine \| Asibitin Jami'a, Linkoeping	Lateral Epicondylalgia (Tennis Elbow)		Ba a Aiwatar da shi ba
NCT02203682	Sun Yat-sen University	Graves Ophthalmopathy\|Cutar Kabari\|Cututtukan Ido\|Cutar Thyroid\|Cututtukan Tsarin Endocrine	Yuli 2014	Mataki na 2
Saukewa: NCT02005653	Majalisar Indiya ta Binciken Likita	Filarial;Kamuwa da cuta	Fabrairu 2009	Mataki na 4
Saukewa: NCT03585140	Centro Dermatológico Dr. Ladislao de la Pascua	Acne Vulgaris \| Gyaran Abinci	1 ga Janairu, 2016	Ba a Aiwatar da shi ba
Saukewa: NCT02147262	Jami'ar Medical Center Ljubljana \| Jami'ar Ljubljana School of Medicine, Slovenia \| Jami'ar Likita ta Vienna \| Jami'ar Harvard	Na kullum Atrophic Acrodermatitis	Yuli 2013	Ba a Aiwatar da shi ba
Saukewa: NCT0220751	Jami'ar Sao Paulo \| Fundação de Amparo à Pesquisa do Estado de São Paulo	Periodontitis \| Nau'in ciwon sukari na 2	Maris 2009	Mataki na 3
Saukewa: NCT01825408	Jami'ar North Carolina, Chapel Hill	Sinusitis	Fabrairu 2013	Mataki na 4
NCT02884713	Asibitin kwararru na Sarki Faisal & Cibiyar Bincike	GASKIYA	Yuni 2013	Ba a Aiwatar da shi ba
Saukewa: NCT02726646	Jami'ar Campinas, Brazil \| Pontificia Universidade Catolica de Sao Paulo	Na kullum periodontitis	Yuni 2015	Mataki na 2
NCT00883818	Samsung Medical Center	Mafitsara mai yawan aiki	Janairu 2007	Mataki na 4
Saukewa: NCT00829790	Teva Pharmaceuticals Amurka	Lafiyayyan	Oktoba 2006	Mataki na 1
NCT01949233	Jami'ar Oxford \| Asibitocin Jami'ar Oxford NHS Trust	Marfan Syndrome	Oktoba 2013	Mataki na 2
Saukewa: NCT01518192	Cibiyar Kiwon Lafiya ta Jami'ar Ljubljana\|Hukumar Bincike ta Sloveniya	Erythema Migrans\|Alamomin Ciwon Bayan Lyme	Yuni 2006	Mataki na 4
Saukewa: NCT02845024	Islamic Azad University, Tehran	Ciwon sukari Mellitus Tare da Ciwon Lokaci	Satumba 2014	Ba a Aiwatar da shi ba
Saukewa: NCT01879930	Asibitin Jami'ar Inselspital, Berne	Likita na zamani na ciwo	Nuwamba 2012	Mataki na 4
Saukewa: NCT00041977	CollaGenex Pharmaceuticals	Kurajen Rosacea	Yuni 2002	Mataki na 3
Saukewa: NCT02341209	Babban Asibitin Rochester	Cutaneous T-cell Lymphoma \| Mycosis Fungoides \| Ciwon Ciki	Fabrairu 6, 2018	Mataki na 2
Saukewa: NCT00002872	Kungiyar Ciwon Kankara ta Gabas	Metastatic Cancer	Nuwamba 1996	Mataki na 3
Saukewa: NCT03162497	Medical University of Vienna	Dry Eye Syndromes \| Meibomian Gland Dysfunction	Janairu 8, 2018	Mataki na 4
Saukewa: NCT01418742	Gesellschaft fur Medizinische Innovation ?Hamatologie und Onkologie mbH\|ClinAssess GmbH	Colourectal Carcinoma	Agusta 2011	Mataki na 2
Saukewa: NCT00980148	Cibiyar Kula da Allergy da Cututtuka (NIAID)	Cutar cututtuka na chlamydial	Disamba 2009	Mataki na 3
Saukewa: NCT03342456	Asibitin Xiangya na Uku na Jami'ar Kudu ta Tsakiya\|Livzon Pharmaceutical Group Inc.\|Yung Shin Pharm.Ind. Co., Ltd.	Duodenal Ulcer Sakamakon Helicobacter Pylori	Disamba 13, 2017	Mataki na 4
Saukewa: NCT04310930	Jami'ar Queensland \| Sashen Lafiya na Gwamnatin Ostiraliya \| Gidauniyar Asibitin Yara \| Gidauniyar Cystic Fibrosis \| Jami'ar Newcastle \| Jami'ar Griffith \| Cibiyar Kiwon Lafiya ta Erasmus \| Jami'ar Monash \| Jami'ar Copenhagen \| Asibitin Cochin \| Cibiyar Nazarin Kiwon Lafiya ta Australiya ta Kudu na Melbourne \| Jami'ar James Cook, Queensland, Australia \| Cibiyar Nazarin Yara na Murdoch	Ciwon Huhu Saboda Mycobacteria (Diagnosis)	Maris 2020	Darasi na 2\|File Na 3
Saukewa: NCT03709459	Cibiyar Kirby \| Cibiyar Nazarin Kiwon Lafiya da Lafiya ta Kudancin Australia \| Jami'ar Monash	Rigakafin STIs	Disamba 17, 2019
Saukewa: NCT04067011	Emergent BioSolutions\|Babban Bincike da Ƙwararrun Ƙwararrun Ƙwararru	Anthrax	12 ga Agusta, 2019	Mataki na 2
Saukewa: NCT02844634	Cibiyar Kula da Cututtuka ta British Columbia	HIV\|Syphilis	Mayu 15, 2018	Mataki na 4
Saukewa: NCT00647959	Mylan Pharmaceuticals	Lafiyayyan	Maris 2006	Mataki na 1
Saukewa: NCT00170222	Cibiyar Lafiya ta Alkmaar	Ciwon huhu Mai Ciki Na Jiki	Yuli 2002	Mataki na 4
Saukewa: NCT03075891	Galderma	Rosacea	Yuli 5, 2017	Mataki na 4
Saukewa: NCT00031499	Cibiyar Kula da Allergy da Cututtuka (NIAID)	Cutar syphilis	Yuni 2000	Mataki na 3
Saukewa: NCT01205464	Jami'ar Linkoeping	Gajiya\|Radicular Pain\|Rashin fahimta	Fabrairu 2005	Ba a Aiwatar da shi ba
Saukewa: NCT01301586	Nexgen Dermatologics, Inc. girma	ACNE VULGARIS	Nuwamba 2010	Darasi Na 1 \| Darasi Na 2
Saukewa: NCT02305940	Yin Karatu a Imperial College London	Cutar Cutar Cutar Cutar Cutar Cutar Cutar Cutar (COPD)	Yuli 2014	Mataki na 3
Saukewa: NCT00351182	Dong-Min Kim \| Asibitin Jami'ar Chosun	Ciwon typhus	Satumba 2005	Mataki na 3
Saukewa: NCT0334682	Asibitin Jami'ar Nantes	Kumburi vulgaris	Janairu 31, 2018	Mataki na 3
Saukewa: NCT01788215	Jami'ar Rochester	Polycystic Ovarian Syndrome (PCOS) \| Hailala marasa daidaituwa	Nuwamba 2010	Mataki na 3
Saukewa: NCT03076281	Sidney Kimmel Cibiyar Cancer a Jami'ar Thomas Jefferson \| Jami'ar Thomas Jefferson	Larynx \| LIP \| Kogon Baki\|Pharynx	Afrilu 3, 2017	Mataki na 2
Saukewa: NCT00439166	Hamilton Health Sciences Corporation \| Gidauniyar Haɗin gwiwar Sabis na Likitoci \| Jami'ar McMaster	Cutar Alzheimer	Fabrairu 2007	Mataki na 3
Saukewa: NCT02463942	Cibiyar Kiwon Lafiya ta Jami'ar Ljubljana\|Jami'ar Ljubljana School of Medicine, Slovenia	Encephalitis mai kaska	Satumba 2014	Ba a Aiwatar da shi ba
Saukewa: NCT00803842	Jami'ar Arewa maso Yamma	Ciwon Kankara Na Huhu Ba Qarami ba	Oktoba 2008	Ba a Aiwatar da shi ba
Saukewa: NCT02086591	Jami'ar Rochester	Yawawar Manya Manyan B-Cell Lymphoma	Maris 2014	Mataki na 2
Saukewa: NCT03980223	Jami'ar California, San Francisco \| Jami'ar Washington \| Cibiyar Nazarin Allergy da Cututtuka (NIAID) \| Mayne Pharma International Pty Ltd \| Sashen Kiwon Lafiyar Jama'a na San Francisco	Gonorrhea \| Chlamydia \| Syphilis	Nuwamba 26, 2019	Mataki na 4
Saukewa: NCT00355459	Jami'ar Texas Southwestern Medical Center	Dry Eye Syndrome	Agusta 2005	Ba a Aiwatar da shi ba
Saukewa: NCT01254799	Omar Mamdouh Shaaban\|Assiut University	Jinin Uterine	Janairu 2008	Mataki na 3
Saukewa: NCT01547325	NanoSHIFT LLC\|Ma'aikatar Tsaro ta Amurka	Raunukan Tiyatarwa	Mayu 2012	Ba a Aiwatar da shi ba
Saukewa: NCT00653380	Par Pharmaceutical, Inc. \| Anapharm	Don Ƙayyade Ma'aunin Halittu Ƙarƙashin Sharuɗɗan Azumi	Satumba 1999	Mataki na 1
Saukewa: NCT00635609	Warner Chilcott	Kumburi vulgaris	Maris 2008	Mataki na 4
Saukewa: NCT03765931	Institut de Recherche pour le Developpement	Zazzaɓi	Yuli 2016	Mataki na 4
Saukewa: NCT01160640	Harold Wiesenfeld \| Cibiyar Nazarin Allergy da Cututtuka (NIAID) \| Jami'ar Pittsburgh	Ciwon Kumburi na Pelvic	Nuwamba 2010	Mataki na 2
Saukewa: NCT01756833	Jami'ar Maryland, Baltimore \| Cibiyar Nazarin tsufa (NIA)	Aneurysm	Mayu 2013	Mataki na 2
Saukewa: NCT00688064	Galderma	Mugun kuraje vulgaris	Agusta 2008	Mataki na 3
Saukewa: NCT01320033	Galderma	Kumburi vulgaris	Maris 29, 2011	Mataki na 2
Saukewa: NCT03397004	St. Michael's Hospital, Toronto\|Barrow Neurological Institute\|Jami'ar Duke \| Cibiyar Nazarin Kiwon Lafiyar Feinstein \| Jami'ar Pittsburgh	Hemorrhagic Telangiectasia (HHT)	Satumba 12, 2018	Mataki na 2
Saukewa: NCT01635530	Asibitin Jami'ar Turku	Lyme Neuroborreliosis	Agusta 2012	Mataki na 4
Saukewa: NCT03727620	Mohammed V Suissi University	m Periodontitis	Janairu 6, 2014	Darasi Na 1 \| Darasi Na 2
Saukewa: NCT02688738	Cibiyar Rothman Orthopedics	Propionibacterium	Maris 2015	Ba a Aiwatar da shi ba
Saukewa: NCT00358462	Jami'ar Washington \| Cibiyar Nazarin Allergy da Cututtuka (NIAID)	Urethritis	Janairu 2007	Mataki na 3
Saukewa: NCT02864550	Cibiyar Kula da Cututtuka ta British Columbia	Syphilis\|cututtukan da ake kamuwa da jima'i	15 ga Agusta, 2019	Mataki na 4
Saukewa: NCT01595594	Jami'ar Sao Paulo \| Fundação de Amparo à Pesquisa do Estado de São Paulo	Ciwon Lokaci \| Nau'in Ciwon Suga Na 2	Maris 2010	Mataki na 3
Saukewa: NCT00964834	PharmAthene, Inc. \| Cibiyoyin Lafiya na Ƙasa (NIH)\|Medarex\|Quintiles, Inc.	Anthrax	Yuli 2009	Mataki na 1
Saukewa: NCT0180944	Sun Yat-sen University	Thyroid Associated Opthalmopathies	Nuwamba 2012	Darasi na 2\|File Na 3
Saukewa: NCT01590082	MD Anderson Cancer Center \| Cibiyoyin Lafiya na Kasa (NIH) \| Cibiyar Ciwon daji ta Kasa (NCI)	Melanoma	Nuwamba 2012	Darasi Na 1 \| Darasi Na 2
Saukewa: NCT00207584	Cibiyoyin Kula da Cututtuka da Cututtuka	Mycoplasma Pneumoniae	Janairu 1994	Ba a Aiwatar da shi ba
Saukewa: NCT00775177	Ranbaxy Laboratories Limited \| Ranbaxy Inc.	Lafiyayyan	Yuni 2005	Ba a Aiwatar da shi ba
Saukewa: NCT03462329	Cibiyar Kiwon Lafiya ta Jami'ar Ljubljana	Erythema Migrans	Yuni 1, 2018	Ba a Aiwatar da shi ba
Saukewa: NCT00000403	Jami'ar Indiana \| Cibiyar Nazarin Arthritis da Musculoskeletal da Skin Cututtuka (NIAMS)	Osteoarthritis	Satumba 1996	Mataki na 3
Saukewa: NCT03508232	Jami'ar Alberta \| Asibitin Royal Alexandra	ST Segment Elevation Myocardial Infarction\|Rashin Zuciya	Janairu 6, 2020	Mataki na 2
Saukewa: NCT02553473	Asibitin Sorlandet HF	Neuroborreliosis, Borrelia Burgdorferi	Oktoba 2015	Mataki na 3
Saukewa: NCT02207556	Kwalejin Kiwon Lafiya ta Wisconsin	Primary Systemic Amyloidosis	Oktoba 1, 2014	Mataki na 2
Saukewa: NCT01783106	Asibitin Jami'ar Royal Liverpool \| Ƙungiyar Ƙasa ta Colitis da Cutar Crohn \| Cibiyar Nazarin Lafiya ta Ƙasa, United Kingdom	Cutar Crohn	Fabrairu 1, 2014	Mataki na 2
Saukewa: NCT00353743	Hospital de Clinicas de Porto Alegre	Zubar da ciki, Septic	Mayu 2006	Ba a Aiwatar da shi ba
Saukewa: NCT01727973	Sun Yat-sen University	Graves Ophthalmopathy\|Cutar Kabari\|Cututtukan Ido\|Cutar Thyroid\|Cututtukan Tsarin Endocrine	Oktoba 2012	Darasi Na 1 \| Darasi Na 2
Saukewa: NCT00857038	Cibiyar Kiwon Lafiya ta Alkmaar \| Cibiyar Kiwon Lafiya ta Jami'ar Leiden \| Jami'ar Amsterdam	Ciwon huhu na Jiki na Ciwon Jiki	Afrilu 2009	Mataki na 4
Saukewa: NCT02774993	Asibitin Jami'ar Kasa, Singapore \| Asibitin Tan Tock Seng \| Jami'ar Kasa, Singapore \| A*Star	Cutar tarin fuka	Satumba 2015	Mataki na 2
Saukewa: NCT03474458	IRCCS Policlinico S. Matteo	Cardiac AL Amyloidosis	Fabrairu 11, 2019	Darasi na 2\|File Na 3
Saukewa: NCT02874430	Sidney Kimmel Cibiyar Cancer a Jami'ar Thomas Jefferson \| Jami'ar Thomas Jefferson	Ciwon daji na nono\|Endometrial Clear Cell Adenocarcinoma	Yuni 8, 2016	Mataki na 2
Saukewa: NCT00016835	Jami'ar Michigan \| Cibiyar Nazarin Dental da Craniofacial Research (NIDCR)	Ciwon Lokaci \| Ciwon sukari Mellitus, Nau'in 2	Oktoba 17, 2001	Mataki na 2
Saukewa: NCT00064766	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Jini na Endometrial \|Cutar lokaci-lokaci	Fabrairu 2003	Mataki na 4
Saukewa: NCT00803452	Jami'ar Louisville	Blepharitis	Yuli 2008	Mataki na 4
Saukewa: NCT01434173	Bayer\|RTI Lafiya Magani	Raunin Hanta da Magani ya jawo	Yuli 2001
Saukewa: NCT00126204	Asibitin Barnes-Jewish	Aortic Aneurysm	Maris 2004	Ba a Aiwatar da shi ba
NCT01917721	Hawaii Pacific Lafiya	Ciwon Kawasaki\|Aneurysm	Oktoba 2013	Mataki na 2
Saukewa: NCT02775695	Kwalejin Kiwon Lafiya ta Wisconsin	Ciwon daji na Pancreatic Mai Sauke	Afrilu 3, 2017	Mataki na 2
Saukewa: NCT03824340	Asibitin Aljazeera	Rashin haihuwa	Janairu 30, 2019	Ba a Aiwatar da shi ba
Saukewa: NCT01847976	Cibiyar Nazarin Asibitin Ottawa \| Gidauniyar Ciwon Kankara ta Kanada	Ciwo	Agusta 2013	Mataki na 2
Saukewa: NCT02850913	Makerere University \| Jami'ar Oxford	Kamewa	Satumba 5, 2016	Mataki na 2
Saukewa: NCT00764361	NanoSHIFT LLC	Ciwon Kafar Kafar Ciwon Suga	Janairu 2009	Mataki na 2
Saukewa: NCT02036528	Royer Biomedical, Inc. girma	Ciwon Qafar Ciwon Suga	Janairu 2014	Darasi Na 1 \| Darasi Na 2
Saukewa: NCT01661985	Majalisar gundumar Ostergotland, Sweden \| Cibiyar Serum ta Jiha	Urethritis \| Cervicitis \| Ciwon ƙwayar cuta na Mycoplasma \| Chlamydia Trachomatis	Fabrairu 2010	Mataki na 4
Saukewa: NCT01380483	Par Pharmaceutical, Inc. \| Anapharm	Don Ƙayyade Ma'aunin Halittu Ƙarƙashin Sharuɗɗan Azumi	Janairu 2000	Mataki na 1
Saukewa: NCT00648180	Mylan Pharmaceuticals	Lafiyayyan	Yuli 2005	Mataki na 1
Saukewa: NCT01426269	Galderma Laboratories, LP	Rosacea	Satumba 2011	Mataki na 4
Saukewa: NCT02753426	Jami'ar California, San Francisco	Ciwon Koda Na Yaudare\|Ciwon Zuciya	Afrilu 2016	Mataki na 1
Saukewa: NCT02583282	Cibiyar Nazarin Ilimin Likita da Bincike ta Digiri na biyu	Maganin Zuciyar Pleural	1 ga Agusta, 2015	Ba a Aiwatar da shi ba
Saukewa: NCT02927496	Task Force for Global Health \| Hukumar Raya Ƙasa ta Amurka (USAID)	Lymphedema \| Lymphatic Filariasis \| Filariasis	Yuni 19, 2018	Mataki na 3
Saukewa: NCT00652795	Par Pharmaceutical, Inc. \| Anapharm	Don Ƙayyade Ma'aunin Halittu Ƙarƙashin Sharuɗɗan Azumi	Yuli 2004	Mataki na 1
NCT03956212	Cibiyar Kiwon Lafiya ta Jami'ar Ljubljana\|Jami'ar Ljubljana School of Medicine, Slovenia	Erythema Migrans	Yuni 1, 2017	Ba a Aiwatar da shi ba
Saukewa: NCT00855595	Bayer	Papulopustular Rosacea	Fabrairu 2009	Mataki na 4
Saukewa: NCT03457636	Derm Research, PLLC	kuraje	Maris 19, 2018	Mataki na 4
Saukewa: NCT02894268	Sir Run Run Shaw Hospital	Helicobacter pylori kamuwa da cuta	Fabrairu 2016	Mataki na 4
Saukewa: NCT03465774	MD Anderson Cancer Center \| National Cancer Institute (NCI)	Maganin Zuciyar Pleural	Maris 8, 2018	Farkon Mataki na 1