Bayani

Sugammadex sodium shine asalin γ-cyclodextrin na roba, kuma yana aiki azaman sabon wakili na juyawa don toshe neuromuscular.

Generic Name: sugammadex (soo GAM ma dex)
Brand Name: Bridion

Sugammadex yana juyar da tasirin wasu magunguna waɗanda ake bayarwa yayin hanyoyin tiyata don shakatawa tsokoki.

Ana amfani da Sugammadex a ƙarshen tiyata, don taimakawa wajen dawo da aikin tsoka da sauran magunguna suka toshe yayin tiyata.

Hakanan ana iya amfani da Sugammadex don dalilai waɗanda ba a lissafa a cikin wannan jagorar magani ba.

Ana amfani dashi don juyar da tasirin wasu magunguna.

In Vivo

Allurar sugammadex ba shi da wani tasiri mai mahimmanci akan hawan jini ko bugun zuciya. Bayan allura na babban adadin rocuronium, 90% dawo da tsarin jirgin ƙasa-na-hudu yana ɗaukar min 28 (SD 7 min) bayan saline, min 26 (SD 9.5 min) bayan 1 mg/kg sugammadex, da 8 min (SD 3.6 min) bayan 2.5 mg/kg summadex [1]. Sugammadex yana haifar da sauri kuma cikakke jujjuyawar toshewar neuromuscular da ke haifar da rocuronium. Lokacin dawowa don horar da rabo huɗu = 0.9 bayan farfadowa na gaggawa shine 14.4 min (SD = 3.4 min; n = 14). Wannan yana raguwa sosai zuwa 3.7 min (SD = 3.3 min; n = 4) tare da summadex 0.5 mg / kg kuma zuwa 1.9 min (SD = 1.0 min; n = 4) tare da summadex 1.0 mg / kg [2]. Kimanin rabin rayuwar sugammadex a cikin biri na Rhesus shine 30 (SEM=4.9) min [3].

Adana

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