Bayani

Sugammadex sodium shine asalin γ-cyclodextrin na roba, kuma yana aiki azaman sabon wakili na juyawa don toshe neuromuscular.

Generic Name: sugammadex (soo GAM ma dex)
Brand Name: Bridion

Sugammadex yana juyar da tasirin wasu magunguna waɗanda ake bayarwa yayin hanyoyin tiyata don shakatawa tsokoki.

Ana amfani da Sugammadex a ƙarshen tiyata, don taimakawa wajen dawo da aikin tsoka da sauran magunguna suka toshe yayin tiyata.

Hakanan ana iya amfani da Sugammadex don dalilan da ba a lissafa a cikin wannan jagorar magani ba.

Ana amfani dashi don juyar da tasirin wasu magunguna.

A cikin Vivo

Allurar sugammadex ba shi da wani tasiri mai mahimmanci akan hawan jini ko bugun zuciya.Bayan allura na babban adadin rocuronium, 90% dawo da tsarin jirgin ƙasa-na-hudu yana ɗaukar min 28 (SD 7 min) bayan saline, min 26 (SD 9.5 min) bayan 1 mg/kg sugammadex, da 8 min (SD). 3.6 min) bayan 2.5 mg/kg summadex [1].Sugammadex yana haifar da sauri da cikakkiyar juyewar toshewar neuromuscular da ke haifar da rocuronium.Lokacin dawowa don horar da rabo huɗu = 0.9 bayan farfadowa na gaggawa shine 14.4 min (SD=3.4 min; n=14).Wannan yana raguwa sosai zuwa 3.7 min (SD = 3.3 min; n = 4) tare da summadex 0.5 mg / kg kuma zuwa 1.9 min (SD = 1.0 min; n = 4) tare da summadex 1.0 mg / kg [2].Kimanin rabin rayuwar sugammadex a cikin biri na Rhesus shine 30 (SEM=4.9) min [3].

Ajiya

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