Pomalidomide, wanda aka fi sani da CC-4047 ko actimid, wani ƙwayar cuta ce mai ƙarfi na immunomodulatory wanda ke nuna aikin antineoplastic don maganin cututtukan cututtukan jini, musamman ma sake dawowa da kuma refractory multiple myeloma (MM). A matsayin abin da aka samu na thalidomide, pomalidomide yana da tsarin sinadari iri ɗaya kamar thalidomide banda ƙari na ƙungiyoyin oxo guda biyu a cikin zoben phthaloyl da ƙungiyar amino a matsayi na huɗu. Gabaɗaya, a matsayin kwayoyin immunomodulatory, pomalidomide yana nuna ayyukan antitumor ta hanyar hanyar toshe microenvironment na ƙari ta hanyar daidaitawar cytokines masu tallafawa ƙari (TNF-α, IL-6, IL-8 da VEGF), kai tsaye yana sarrafa mahimman ayyukan ƙari. sel, da kuma tallafawa tallafi daga ƙwayoyin sel marasa rigakafi.

Ana amfani da Pomalidomide don magance myeloma da yawa (ciwon daji da ke fitowa daga ci gaba da cutar jini). Yawancin lokaci ana ba da Pomalidomide bayan an gwada aƙalla wasu magunguna biyu ba tare da nasara ba.

Ana kuma amfani da Pomalidomide don magance cutar kanjamau mai alaƙa da Kaposi sarcoma lokacin da wasu magunguna ba su yi aiki ba ko kuma sun daina aiki. Hakanan ana iya amfani da pomalidomide don magance Kaposi Sarcoma a cikin manya waɗanda sukeHIV- mara kyau.

Pomalidomide yana samuwa ne kawai daga ƙwararrun kantin magani a ƙarƙashin wani shiri na musamman. Dole ne a yi muku rajista a cikin shirin kuma ku yarda don amfanihana haihuwamatakan kamar yadda ake bukata.

Hakanan ana iya amfani da Pomalidomide don dalilan da ba a lissafa a cikin wannan jagorar magani ba.

Pomalidomide na iya haifar da lahani mai tsanani, mai barazana ga rayuwa ko mutuwar jariri idan uwa ko uba suna shan pomalidomide a lokacin daukar ciki ko lokacin daukar ciki. Ko da kashi ɗaya na pomalidomide na iya haifar da manyan lahani na hannun jarirai da ƙafafu, ƙashi, kunnuwa, idanu, fuska, da zuciya. Kada kayi amfani da pomalidomide idan kana da ciki. Faɗa wa likitan ku nan da nan idan jinin haila ya makara yayin shan pomalimide.