Bayani

Calcium Pitavastatin (NK-104 hemicalcium) shine mai hanawa mai hana hydroxymethylglutaryl-CoA (HMG-CoA).Calcium Pitavastatin (NK-104 hemicalcium) yana hana haɗin cholesterol daga acetic acid tare da IC50 na 5.8 nM a cikin sel HepG2.Calcium Pitavastatin shine ingantacciyar ƙwayar hepatocyte low-density lipoprotein-cholesterol (LDL-C).Ayyukan rigakafin ciwon daji.

Fage

Calcium Pitavastatin shine mai hanawa ga enzyme HMGCR (HMG-CoA reductase) yana haifar da raguwa a cikin haɗin LDL cholesterol.Wani bincike ya nuna cewa pitavastatin na iya kashe iskar oxygen a cikin sel na endothelial ta hanyar hana NADPH oxidase.Bugu da ƙari, pitavastatin yana rage bayyanar eNOS mRNA yayin da yake ƙara NO dogara da amsa ta hanyar acetylcholine da calcium ionophore, A23187.Bugu da ƙari, pitavastatin yana hana haɓaka tsarin tafiyar da tashoshi na potassium mai kunna calcium ta hanyar rage matakan cholesterol a cikin sel.

Ajiya

4°C, kariya daga haske

*Cikin karin ruwa:-80°C, watanni 6;-20°C, wata 1 (kare haske)

Tsarin sinadaran

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