Bayani

Calcium Pitavastatin (NK-104 hemicalcium) shine mai hanawa mai hanawa na hydroxymethylglutaryl-CoA (HMG-CoA). Calcium Pitavastatin (NK-104 hemicalcium) yana hana haɗin cholesterol daga acetic acid tare da IC50 na 5.8 nM a cikin sel HepG2. Calcium Pitavastatin shine ingantacciyar ƙwayar hepatocyte low-density lipoprotein-cholesterol (LDL-C). Ayyukan rigakafin ciwon daji.

Fage

Calcium Pitavastatin shine mai hanawa mai hana enzyme HMGCR (HMG-CoA reductase) yana haifar da raguwa a cikin haɗin LDL cholesterol. Wani bincike ya nuna cewa pitavastatin na iya hana samar da iskar oxygen a cikin ƙwayoyin endothelial ta hanyar hana NADPH oxidase. Bugu da ƙari, pitavastatin yana rage bayyanar eNOS mRNA yayin da yake ƙara NO dogara da amsa ta hanyar acetylcholine da calcium ionophore, A23187. Bugu da ƙari, pitavastatin yana hana haɓaka tsarin tafiyar da tashoshi na potassium mai kunna calcium ta hanyar rage matakan cholesterol a cikin sel.

Adana

4°C, kariya daga haske

*Cikin kaushi:-80°C, watanni 6; -20°C, wata 1 (kare haske)

Tsarin sinadaran

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