Vericiguat
Vericiguat ni apyrazolopyridinewato5-fluoro-1H-pyrazolo [3,4-b] pyridineA cikinsa an maye gurbin amino hydrogen a matsayi na 1 ta ƙungiyar 2-fluorobenzyl kumahydrogena matsayi na 3 an maye gurbinsu ta hanyar 4,6-diamino-5-[(methoxycarbonyl) amino] pyrimidin-2-yl rukuni. Yana da mai narkewaguanylatecyclase stimulator wanda ake amfani dashi don maganin ciwon zuciya na kullum. Yana da matsayi a matsayin mai narkewaguanylatecyclase activator, wani vasodilator wakili da antihypertensive wakili. Yana da waniaminopyrimidine, apyrazolopyridine, da ester carbamate da organofluorine fili.
Vericiguat yana ƙarƙashin bincike a cikin gwaji na asibiti NCT02861534 (Nazarin Vericiguat a cikin Mahalarta Tare da Rashin Ciwon Zuciya Tare da Rage Ƙarfafa Ƙaddamarwa (HFrEF) (MK-1242-001)).
Vericiguat Mai Soluble neGuanylateCyclase Stimulator. Hanyar aikin vericiguat kamar aGuanylateCyclase Stimulator.
Vericiguat magani ne da ake amfani dashi don sarrafawa da kuma magance raunin zuciya tare da rage juzu'in fitar da jini (HFrEF). Yana da amfani ga ciwon zuciya mai rauni na yau da kullun, rashin raunin zuciya kwanan nan. Vericiguat baya tsawaita rayuwa amma yana hana sake dawowa. Wannan aikin yana bayyana alamun, tsarin aiki, kashi, da kuma yanayin gudanarwa ta ƙungiyar masu sana'a, illa mara kyau, contraindications, da gwaje-gwaje da yawa don tallafawa shaidar amfani da miyagun ƙwayoyi a cikin HFrEF.





Shawara18Ayyukan Ƙididdigar Ingancin Ingancin waɗanda suka amince4, kuma6ayyukan suna ƙarƙashin amincewa.

Babban tsarin kula da ingancin ingancin ƙasa da ƙasa ya kafa tushe mai ƙarfi don siyarwa.

Ingantattun kulawa yana gudana cikin duk tsawon rayuwar samfurin don tabbatar da inganci da tasirin warkewa.

Mawakan da ake gudanarwa na kwararru yana tallafawa ingancin bukatun yayin aikace-aikacen da rajista.


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