Crisaborole
Crisaborole memba ne na aji na benzoxaboroles wanda shine 5-hydroxy-1,3-dihydro-2,1-benzoxaborole wanda a ciki yana da phenolic.hydrogenAn maye gurbinsu da ƙungiyar 4-cyanophenyl.A phosphodiesterase 4 inhibitor da ake amfani da shi don maganin m zuwa matsakaici atopic dermatitis a cikin yara da manya.Yana da matsayi a matsayin mai hana phosphodiesterase IV, anantipsoriaticda kuma magungunan da ba na steroidal anti-inflammatory ba.Yana da benzoxaborole, ether mai ƙanshi da nitrile.
Crisaborole labari neoxaboroleFDA ta amince da shi a ranar 14 ga Disamba, 2016 azaman Eucrisa, magani na kan layi na ga m zuwa matsakaici atopic dermatitis.Wannan wakili ba na steroidal ba yana da tasiri wajen inganta ƙwayar cuta, rage haɗarin kamuwa da cuta da rage alamun da alamun cututtuka a cikin marasa lafiya 2 shekaru da haihuwa.Yana rage ƙumburi na gida a cikin fata kuma ya hana kara tsananta cutar tare da kyakkyawan bayanin martaba.Tsarinsa ya ƙunshi aboronatom, wanda ke sauƙaƙe shigar fata da ɗaure zuwa cibiyar bimetal na phosphodiesterase 4 enzyme.A halin yanzu ana ci gaba da haɓakawa azaman maganin cututtukan fata na psoriasis.
Crisaborole shine mai hanawa phosphodiesterase 4.Tsarin aikin crisaborole shine azaman mai hanawa na phosphodiesterase 4.
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